Corning Matrigel matrix is a solubilized basement membrane preparation extracted from the Engelbreth-Holm-Swarm (EHS) mouse sarcoma, a tumor rich in extracellular matrix proteins, including Laminin (a major component), Collagen IV, heparin sulfate proteoglycans, entactin/nidogen, and a number of growth factors.
Mouse colonies routinely screened for pathogens via Mouse Antibody Production (MAP) testing
Extensive PCR testing is performed to screen for a number of pathogens
Tested and found negative for bacteria, fungi, and mycoplasma
Protein concentrations determined by Lowry method
Endotoxin units measured by Limulus Amoebocyte Lysate assay
Matrigel Matrix gel stability is tested for a period of 14 days at 37°C
Biological activity is determined for each lot using a neurite outgrowth assay.
Engelbreth-Holm-Swarm Mouse Tumor
Preparation and Storage
Store at -20°C. Avoid multiple freeze-thaws. Do not store in frost-free freezer. KEEP FROZEN.
Cell Growth and Differentiation
in vitro and in vivo Angiogenesis Assays
in vivo Angiogenesis Studies and Augmentation of Tumors in Immunosuppressed Mice
Click here for Corning Matrigel Lot Selection and Reservation.